Parkinson’s Disease Prediction Based on Multistate Markov Models

Authors

  • Hariton Costin Grigore T. Popa University of Medicine and Pharmacy, Iasi
  • Oana Geman Faculty of Electrical Engineering and Computer Science, Stefan cel Mare University of Suceava Development and Human Health Department

Keywords:

Parkinson’s disease, Markov chains, Multistate Markov Models, Prediction.

Abstract

In the real medical world, there are many symptoms or chronic diseases that cannot be characterized in a deterministic way, and which must be examined in a random way. In the study of these stochastic processes, Markov chains are used. There is a wide variety of phenomena that suggest a behavior in a Markov process manner such as: the probability that a patient's health to improve, to get worse, to remain stable or to progress to death within a certain time slot, depending on what happened in the previous time window. Our goal is to show that the Markov chains can be applied to the patients with Parkinson’s disease in order to predict the evolution of the disease over time. So the doctor may decide a therapeutic solution that is adapted to the patient's needs, and that can improve the quality of the patient's life with Parkinson's disease in terminal stage.

Author Biography

Hariton Costin, Grigore T. Popa University of Medicine and Pharmacy, Iasi

Hariton Costin, BS in Electronics and Telecom, Ph.D. in Applied Informatics, MBA diploma, is full professor at the University of Medicine and Pharmacy/Faculty of Medical Bioengineering, Iasi, Romania. He is also senior researcher at the Romanian Academy-Iasi Branch, Institute of Computer Science, the Image Processing and Computer Vision Lab.

Competence areas:medical electronics, biosignal and image processing, artificial intelligence, telemedicine and e-health.

Scientific and research activity:about 110 published papers, 8 books, 4 book chapters, 3 patents, 2 national awards, 36 research reports, technical manager within FP5/INES 2001-32316 project, director of the first Romanian telemedical pilot center in Iasi, director for 9 granted projects in bioengineering, postdoc researcher at the USTL of Lille (France), invited talks at international conferences. Prof. Costin is a member of the IEEE-EMBS and of other 6 scientific societies.

 

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Published

2013-07-12

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